After the Cuban Revolution, Che is at the height of his fame and power. Then he disappears, re-emerging incognito in Bolivia, where he organizes a small group of Cuban comrades and Bolivian recruits to start the great Latin American Revolution. Through this story, we come to understand how Che remains a symbol of idealism and heroism that lives in the hearts of people around the world.

The Argentine, begins as Che and a band of Cuban exiles (led by Fidel Castro) reach the Cuban shore from Mexico in 1956. Within two years, they mobilized popular support and an army and toppled the U.S.-friendly regime of dictator Fulgencio Batista.